Breakthrough in Cannabis Curing Cancer Research

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Breakthrough in Cannabis Curing Cancer Research

Recent research on cannabis curing cancer has uncovered the exact mechanisms through which this phenomenon is possible. Whispers that cannabis kills cancer cells have been floating around communities for years without any hard evidence, yet those thoughts are slowly being backed up by research. There are over 60 cannabinoids in Cannabis Sativa, of which cannabidiol (CBD), THC, cannabinol, cannabigerol and cannabichromene are present in reasonably high quantities.

Of these, cannabidiol has been shown to possess no psychoactive effects and has been the prime focus of cannabis curing cancer research. Yet to name a few of its characteristics it is an anxiolytic, antioxidant,  neuroprotective agent, anti-convulsant, anti-arthritic agent and immune modulator.

 

Cannabis Curing Cancer – The Endocannabinoid System

Cannabinoids exert their effects depending on the tumor cell type. Synthetic cannabinoids coupled with the endocannabinoid system inhibit cancer cell proliferation and new blood vessels formation within tumors, thus minimizing tumor growth and invasion into healthy tissue,  while also inducing tumor cell death. Cannabis kills cancer cells by coupling its effects to the endocannabinoid system.

The endocannabinoid system is abnormally regulated in certain physiological conditions, state that allows cancer cells to multiply and migrate. This is an important realization, making the endocannabinoid system a very attractive and potent target for cannabis curing cancer research and pharmacological intervention for the treatment of various types of cancer. It is also important to note that cannabinoids exert their effect specifically on tumor cells, without having any detrimental impact on normal cells.

Firstly, endocannabinoids are naturally occurring bioactive lipids within our bodies. Their Cannabis curing cancer research - endocannabinoid systemactivities are mainly mediated by two receptor – CB1 and CB2. The endocannabinoids together with their receptors and the proteins that are responsible for their production, transport and degradation make up the endocannabinoid system.

This system is responsible for regulating numerous functions within the body including:

  • Metabolism
  • Reproduction
  • Immunity
  • Neuronal activity
  • Cardiovascular tone

Manipulating this system by administering synthetic cannabinoids is being recognized as a very promising tactic for treating many diseases and has been the focus of cannabis curing cancer research.

When cannabinoids are introduced into the body, their effect is regulated by these two
receptors. The CB1 receptor is mainly located in the central nervous system and is responsible for mediating psychotropic(pain relief, temperature control, movement etc.) effects of external cannabinoids such as THC (the active compoCannabis curing cancer research - endocannabinoid systemnent of marijuana).

The CB2 receptor is located in inflammatory tissue and is responsible for delivering the anti-inflammatory effects of external cannabinoids.

 

Many studies have shown that cannabinoids coupled with the endocannabinoid system directly suppress tumor growth in vitro and in animal tumor models through several different pathways. Tumor growth and progression have been shown to be inhibited by synthetic and natural cannabinoids in numerous types of cancers such as:

  • Glioblastoma
  • Glioma
  • Breast and Prostate cancer
  • Colon carcinoma
  • Thyroid cancer
  • Leukemia
  • Lymphoid tumors

Cannabis kills cancer by halting tumor progression through different mechanisms and at various levels. At least one of the following mechanism has been observed in all cancer types that have been tested.

 

Cannabis Curing Cancer  – The Mechanisms

Cannabinoids Induce Tumor Cell Death

THC  has proven to induce targeted cell death by inhibiting survivin signaling and overexpression in colorectal cancer. Survivin is a protein that prevents cell death and is normally only present in extremely small amounts in the adult body, yet it is over-expressed in most tumors and has been associated with poor treatment outcomes in cancer patients.Cannabis curing cancer - tumor cell death

Another mechanism through which cannabis kills cancer cells is by stimulating the production of ceramide in human cancer cells.

Ceramide is a lipid that regulates several stress proteins and genes that exert their effect on a molecular level. High levels of ceramide have been associated with an increased percentage of cell death in human glioma, leukemia, pancreatic and colorectal cancer.

 

Cannabinoids Inhibit Tumor Proliferation

Cannabinoids have shown to inhibit tumor growth by directly impacting the pathways through which tumor cells proliferate. They trigger the activation of several enzymes, inhibit the activity of growth factors and modulate receptor responses within the tumor cells.

To be more specific, CBD increases cellular Calcium levels leading to  a production of reactive oxygen species. These reactive oxygen species damage cellular proteins, lipids, and DNA, ultimately leading to fatal lesions and cell death.

Reactive oxygen species have different effects depending on the metabolic rate of a cell. Tumor cells have a high basal metabolic rate, making them extremely susceptible to damage induced by these oxidative species, this being one of the main mechanisms through which cannabis kills cancer cells.

More information can be found here.

Cannabinoids Inhibit the Formation of New Blood vessels within Tumors

The formation of new blood vessels is a pivotal step in the growth and development of solid tumors. A staggering number of studies have shown that cannabinoids also influence tumor growth by inhibiting growth factors and directly lowering the density of blood vessels within the tumor.

Cannabinoids directly lower the number and size of cells thCannabis curing cancer - blood vessels tumorat form new blood vessel within the tumor, but also their survival and migration rate.

During animal trials, rats suffering from glioma, skin cancer and lung cancer that had treatments with cannabinoids presented small, pale tumors, that had a fragile and poorly developed vascular network. Thus, by actively limiting their blood supply, cannabis kills cancer cells.

More information can be found here.

 

Cannabinoids Inhibit Tumor Cell Migration

An important part of the spreading of cancer is the migration of tumor cells. Initially, the primal tumor enters the blood or lymphatic vessels. Cancer cells migration is prompted by chemoattractants  and influenced by neurotransmitters.

Within the body, mast cells are a prime source of chemoattractants and incidentally they are also the targets of cannabinoids. These chemoattractants exert their influence through growth factors. As mentioned before, cannabinoids have been shown to modulate the activity of growth factors,  and thus preventing the migration of tumor cells.

It is also very well known that cannabinoids affect the activity of neurotransmitters. They can also inhibit cancer cell migration that is triggered by a norepinephrine release.

More information can be found here.

 

Cannabinoids Influence Cancer Cell Adhesion

Tumor cells have an adhesive interaction with the microenvironment that surrounds them, that is essential for their proliferation, migration and metastasis. Cannabinoids decrease the affinity of cancer cells towards the proteins that make up the cell matrix and external layers of healthy cells that surround them.

They have been shown to reduce the adhesion of breast cancer cells to collagen components. They also decrease the affinity of cancer cells for healthy tissue in specific cancer types such as neuroblastoma, glioblastoma and lymphoma.

More information can be found here.

 

Cannabinoids Inhibit Tumor Cell Invasion

CBD has been shown to halt tumor cell invasion into local healthy tissue, as well as metastasis by directly shutting down the action of a pro-metastatic gene Id1. This action was observed in both animal and human models of breast and brain cancer. Id1 has been identified as essential for the progression and metastasis of breast cancer.  By limiting the expression of this gene, CBD interferes with tumor cell invasion.Cannabis curing cancer research - cell invasion

Another mechanism through which CBD inhibits tumor cell invasion and growth is by affecting the microenvironment of the tumor.

Chemical signaling between tumor cells and healthy tissue is interrupted and enzymes that degrade the extracellular matrix are inhibited by the CBD activity. These encouraging findings have been confirmed in human breast cancer cells.

More information can be found here.

 

Author’s Note on Cannabis Curing Cancer Research

For years there have been numerous claims that cannabis kills cancer cells and yet science is only just beginning to understand the mechanisms through which this is possible. It is still a very controversial subject as the use of Cannabis Sativa is still considered to be only for “personal entertainment” and has little medical practice. Yet, the cannabis curing cancer research is working hard to provide us with better knowledge and understanding of the potential of this herb.

If you would like more information on the medical effects of Cannabis we recommend you take a look at our article on the Benefits of Marijuana Juice, CBD for Parkinson’s Disease and Medical Marijuana for Hypothyroidism.

You might also like our study regarding the Effects of Ketamine Infusion Treatment on Depression.

If you would like more details on the subject or if you have any questions, objections, hateful comments or highly deserved praises to offer please do not hesitate to leave a comment.

Also, if you have a product that you would like me to review and research, I gladly welcome the challenge.

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6 COMMENTS

  1. I was diagnosed of cancer which was critical in my case. It was as if my world had come to an end cause the doctor told me that it was only by the grace of the Almighty that I was alive. I was given few weeks to live but the pains I went through made each day feel like the last day and I was so scared to leave this earth. It was when i visited my aunt in California she told me about Rick Simpson cannabis oil, she told me she heard her friend’s mom talking about it, then i purchased the oil and I have being following the dosage that I was given for the past two months and there has being improvement in my health, I no longer feel pains and I wake up revived, energized. If you are going through this issue, do contact his EMAIL:(Ricksimpsoncannaoilservice@gmail.com)

  2. No clinical trials of Cannabis as a treatment for cancer in humans has been undertaken Please show how it cures Cancer as it would take someone to be cancer free for 5 years to say there is a cure and the fact the first human cancer clinical study has only just started how do you say it cures cancer

  3. I also have a story, my mom was diagnosed with stage 3 c ovarian cancer. We were scared. It was metastasized and inoperable.  The Dr said there was nothing they could do.  She began taking cbd oil on April 4th of this year. She was in very bad shape, she was so sick, she was in a wheelchair and could not do anything but take her oil and eat a bit. Her cancer marker number began at 1590.  3 weeks later her number was 670!!! We couldn’t believe it! On may 23 she went on vacation with her friends!  That was 6 weeks after being in a wheel chair very sick.  And 3 weeks ago she was cancer free! On that day I Knew I  had to tell the world! I now sell that cbd oil! We are convinced! Ours is sunshine global, it’s cold pressed, organic and iso certified. It does not have thc or get you high. It’s the purest and best on the market. Ours has 400 mgs, 700mgs, 1800mgs 2500mgs and something new called full spectrum.  These mg dosages are incredibly strong and work fast. It could stop a seizure in its tracks! Prices are 300.00 for the cancer grade and they go down in 50.00 increments. This oil has worked for my mom who had it bad..
    Thank you for your time I would love to hear your thoughts!
    Patty Prince 802-598-4524,

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